Re: Where is the evidence for the existence of the "HIV" genome 25 August 2004
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Christopher J Noble,
postdoc
Australia

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Re: Re: Where is the evidence for the existence of the "HIV" genome

The Perth Group write:Would Christopher Noble please give us one reference, and a few confirmatory studies, by Gallo, Montagnier or any other "HIV" expert with evidence for the existence of the whole "HIV" genome and not just "HIV" sequences in fresh, uncultured lymphocytes of AIDS patients.

Already the goal posts have moved. Initially, it was about whether HIV DNA has been found in T-cells. Several qualifications have been added. I expect more will follow.

Gallo reported finding HIV DNA in PBMCs in 1984. Molecular characterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome.

This study did indicate that only a small number of T-cells are infected with HIV and that lymph nodes and spleen cells are a better place to look. The Perth Group are already aware of this paper and choose to ignore it.

I do not believe that the Perth Group will be easily separated from their dogma by evidence. Nevertheless, I will play their game. Here is a reference showing full length HIV genomes (minus the 5' LTR) recovered form various tissue cells including PBMCs, lymph nodes and spleen cells. Biological characterization of human immunodeficiency virus type 1 clones derived from different organs of an AIDS patient by long-range PCR.

Competing interests: None declared